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Metabolic

GLP-3(R)

≥99.3% HPLC Verified Purity
CAS Number2381089-83-2
Molecular Weight4731.33 g/mol
Molecular FormulaC221H342N46O68
Storage-20 °C, lyophilized
$40.00/ vial
1
RESEARCH USE ONLY: This compound is intended exclusively for in vitro laboratory research. Not for human or veterinary use. Not intended to diagnose, treat, cure, or prevent any disease. Not evaluated by the FDA. Must be 21+ to purchase.
GLP-3(R)

What is GLP-3?

GLP-3 is a retatrutide-class GLP-1/GIP/glucagon triple receptor agonist research peptide with the molecular formula C₂₂₁H₃₄₂N₄₆O₆₈ and a molecular weight of 4731.33 Da (CAS: 2381089-83-2), studied in pancreatic beta-cell and adipocyte models for concurrent GLP-1R, GIPR, and glucagon receptor signal transduction. Supplied at ≥99.3% HPLC purity as a lyophilized powder for in vitro research use only.

Amino Acid Sequence:Proprietary triple-receptor agonist sequence
Classification: Triple GLP-1/GIP/Glucagon Receptor AgonistGLP-1 Receptor (GLP-1R)GIP Receptor (GIPR)Glucagon Receptor (GCGR)

Specifications

CAS Number2381089-83-2
Molecular FormulaC221H342N46O68
Molecular Weight4731.33 g/mol
Purity≥99.3% (HPLC verified)
FormLyophilized powder
Storage-20 °C, lyophilized
ShippingInsulated protective packaging

Mechanism of Action

Triple Receptor Co-Agonism

GLP-1R/GIPR/GCGR simultaneous activation

GLP-3 activates three incretin/glucagon receptors concurrently, engaging distinct cAMP pathways in beta-cell and adipocyte culture models.

Storage & Handling

Temperature:-20°C for long-term storage
Light Sensitivity:Protect from direct light
Stability Duration:Stable for 24 months when stored properly
Research-grade sequence verification via standard assays.

Related Compounds

Research Use Only

All compounds are sold strictly for laboratory research use. Not for human use. These products are not drugs, supplements, or food. Statements have not been evaluated by the FDA. Must be 21+ to purchase. This compound is intended exclusively for in vitro laboratory research. Not for human or veterinary use. Not intended to diagnose, treat, cure, or prevent any disease.

Related Research Compounds

5-Amino-1MQ
Metabolic

5-Amino-1MQ

CAS:42464-96-0
Formula:C10H11N2 (free base)
MW:159.21 g/mol (free base)
$35.00 / vial
For in vitro research use only. Not for human use.
AICAR
Metabolic

AICAR

CAS:2627-69-2
Formula:C9H14N4O5
MW:258.23 g/mol
$60.00 / vial
For in vitro research use only. Not for human use.
AOD9604
Metabolic

AOD9604

CAS:386264-39-7
Formula:C78H123N23O23S2
MW:1815.12 g/mol
$50.00 / vial
For in vitro research use only. Not for human use.

Scientific Context

Related Research & Analysis

Retatrutide

Retatrutide (GLP-3): Molecular Structure, Receptor Pharmacology, and Research Overview

A research overview of retatrutide, a synthetic triple receptor agonist studied for its activity at the GIP, GLP-1, and glucagon receptors. Covers molecular structure, receptor pharmacology, and how it differs from single-target GLP-1 receptor agonists. For research purposes only.

Read Full Article
Metabolic

Comparative Pharmacodynamics of Metabolic Peptides: GLP-1, GIP, and Dual Agonist Research

A research-focused comparison of GLP-1, GIP, and dual GIP/GLP-1 agonist peptides including tirzepatide, examining receptor binding, metabolic mechanisms, and published research outcomes.

Read Full Article