What is GLP-1(S) used for?

GLP-1(S) is a synthetic peptide compound studied in laboratory research settings. It has molecular formula C187H291N45O59, a molecular weight of 4113.58 g/mol, CAS 910463-68-2. Published preclinical research has documented its interactions with the GLP-1 Receptor, G-Protein Coupled Receptor. It is intended for in vitro research use only and is not approved for human consumption.

What purity level does Amino Foundry's GLP-1(S) have?

Amino Foundry supplies GLP-1(S) at ≥99% purity, verified by third-party HPLC and mass spectrometry analysis. Certificates of Analysis are available upon request.

How is GLP-1(S) supplied?

GLP-1(S) is supplied as a lyophilized powder in sealed research-grade vials, intended for in vitro and laboratory research use only.

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Metabolic

GLP-1(S)

Name: GLP-1(S)
Brand: Amino Foundry
SKU: AF-GLP1S

≥99% HPLC Verified Purity

CAS Number910463-68-2

Molecular Weight4113.58 g/mol

Molecular FormulaC₁₈₇H₂₉₁N₄₅O₅₉

Storage-20 °C, lyophilized

$50.00/ vial

In stock · Ships in 1-2 business days

RESEARCH USE ONLY: This compound is intended exclusively for in vitro laboratory research. Not for human or veterinary use. Not intended to diagnose, treat, cure, or prevent any disease. Not evaluated by the FDA. Must be 21+ to purchase.

What is Semaglutide?

Semaglutide is a synthetic analog of human glucagon-like peptide-1 (GLP-1) with 94% homology to native GLP-1. With the molecular formula C₁₈₇H₂₉₁N₄₅O₅₉ and a molecular weight of 4113.6 g/mol (CAS: 910463-68-2), Semaglutide incorporates a C18 fatty di-acid side chain attached to lysine at position 26 and modified amino acid substitutions at positions 8 (Aib), 34 (Arg), and a truncated C-terminus.

Amino Acid Sequence:

His-Aib-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Val-Ser-Ser-Tyr-Leu-Glu-Gly-Gln-Ala-Ala-Lys(AEEA-AEEA-γ-Glu-eicosanedioic acid)-Glu-Phe-Ile-Ala-Trp-Leu-Val-Arg-Gly-Arg-Gly

Classification: GLP-1 Receptor AgonistGLP-1 ReceptorG-Protein Coupled Receptor

Specifications

CAS Number	910463-68-2
Molecular Formula	C187H291N45O59
Molecular Weight	4113.58 g/mol
Purity	≥99% (HPLC verified)
Form	Lyophilized powder
Storage	-20 °C, lyophilized
Shipping	Insulated protective packaging

Mechanism of Action

GLP-1 Receptor

Gs-protein coupling

Semaglutide binds to GLP-1 receptors with high affinity, activating Gs-proteins and increasing intracellular cAMP levels in beta-cell models.

Albumin Binding

Lipophilic side chain interaction

The C18 fatty di-acid side chain enables reversible albumin binding, extending circulation half-life in biochemical studies.

Receptor Internalization

Endocytosis/recycling

Published studies indicate Semaglutide promotes receptor internalization with distinct kinetics compared to native GLP-1.

Storage & Handling

Temperature:-20°C for long-term storage

Light Sensitivity:Protect from direct light

Stability Duration:Stable for 24 months when stored properly

Lyophilized powder is stable for extended periods; protect from moisture.

Related Compounds

Cagrilintide Mazdutide GLP-2(T)

Research Use Only

All compounds are sold strictly for laboratory research use. Not for human use. These products are not drugs, supplements, or food. Statements have not been evaluated by the FDA. Must be 21+ to purchase. This compound is intended exclusively for in vitro laboratory research. Not for human or veterinary use. Not intended to diagnose, treat, cure, or prevent any disease.

Scientific Context

Research Cart

GLP-1(S)

What is Semaglutide?

Specifications